Cosmos - Revision history

Admin at 11:59, 22 October 2025

2025-10-22T11:59:11Z

← Older revision		Revision as of 11:59, 22 October 2025
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	'''EU Programme:'''		'''EU Programme:'''
	[[Programme::Horizon 2020]]		[[Programme::Horizon 2020]]

			[[ItemType::EU Project]]

Admin at 12:54, 21 October 2025

2025-10-21T12:54:16Z

← Older revision		Revision as of 12:54, 21 October 2025
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	==[[EU Project short name::Cosmos]]==		==[[EU Project short name::Cosmos]]==
	===[[EU Project full name::~~Connectome cost conservation model of skill learning~~]]===		===[[EU Project full name::DevOps for Complex Cyber-physical Systems]]===
	'''Full project details (EU Research results portal):''' [[CORDIS URL::https://cordis.europa.eu/project/id/~~661484~~]]		'''Full project details (EU Research results portal):''' [[CORDIS URL::https://cordis.europa.eu/project/id/957254]]

	=== '''Project description:''' ===		=== '''Project description:''' ===
	~~Diseases~~ of the ~~heart~~ and ~~circulatory system are the main cause~~ of ~~death in Europe (over 4 million deaths each year). In particular~~, ~~heart failure (HF) accounts~~ for ~~almost 1~~.~~1 million deaths each year. In early ’90 there was~~ the ~~formal recognition that inflammatory mediators are activated~~ in the ~~setting~~ of ~~HF by a sentinel description~~ of ~~inflammatory cytokines in patients with heart failure~~. ~~After that,~~ a ~~growing interest in the role~~ of ~~biomarkers in regulating cardiac structure~~ and ~~function~~, ~~particularly regarding their potential role in disease progression in heart failure~~, ~~raised up. Nowadays, there are evidences on that. Generally~~, ~~biomarkers are determined mostly~~ in ~~plasma or in blood, rather than in saliva~~. ~~In fact~~, ~~despite of that very few of them have been currently studied in saliva, saliva has to~~ be ~~considered as an important diagnostic and prognostic medium for minimally invasive tools~~. ~~Indeed a great progress in disclosing the complete salivary proteome has carried~~ to ~~the identification of more than 3000 different proteins. Scope of this project is~~ to ~~develop a tool for HF-biomarkers detection through saliva. The idea is to combine the knowledge~~ of the ~~experienced researcher in microelectronics~~ and ~~CMOS imagers with the competences of the hosting laboratory on bioMEMs for biomarkers immobilization~~ to ~~develop an innovative point-of-care system for a fast and precise detection of HF-biomarkers~~. ~~To this end~~ the ~~hosting institution and~~ the ~~experienced researcher complete each other~~ and ~~make the research and development on this cross related filed feasible~~. ~~The proposed device~~ will ~~allow a mass screening for~~ the ~~prevention of HF~~ and ~~other pathologies related to the cardiovascular system~~.~~Within this project,~~ the ~~experienced researcher~~ will be ~~able both~~ to ~~enlarge her knowledge in~~ the ~~design~~ of ~~CMOS imagers by implementing innovative photon detection techniques~~ and to ~~approach a growing branch of microelectronics, such as the bioMEMs one~~.		Much of the increasing complexity of ICT systems is being driven by the more distributed and heterogeneous nature of these systems, with Cyber Physical Systems accounting for an increasing portion of Software Ecosystems. This basic premise underpins the COSMOS proposal which focuses on blending best practices DevOps solutions with the development processes used in the CPS context: this will enable the CPS world to deliver software more rapidly and result in more secure and trustworthy systems.COSMOS brings together a balanced consortium of big industry, SMEs and academics which will develop enhanced DevOps pipelines which target development of CPS software. These pipelines will integrate more sophisticated validation and verification (V&V) which will comprise of a mix of static code analysis correlated with issues and bug reports, automated test case generation, runtime verification, Hardware in the Loop (HiL) testing and feedback from field devices. Approaches based on Machine Learning, model based testing and search based test generation will be employed. Techniques to prioritize and schedule testing to maximize efficacy of the testing process and to minimize security threats will also be developed. COSMOS will leverage existing prototype technologies developed by the partners supporting enhancing them throughout the project.The COSMOS CPS pipelines will be validated against 5 use cases provided by industrial partners representing healthcare, avionics, automotive, utility and railway sectors. These will act as reference use cases when promoting the technology amongst Open Source and standardization communities. For the former a specific community building activity will be performed to stimulate engagement with Open Source; for the latter, the standards experience of the coordinator and partners will be employed to promote COSMOS technologies within heavily regulated sectors where there is an increasing need for well-defined software V&V solutions.

	'''EuroVoc IDs:''' [[EuroVoc ID::/natural sciences/~~biological~~ sciences/~~biochemistry/biomolecules/proteins/proteomics~~]]		'''EuroVoc IDs:''' [[EuroVoc ID::/natural sciences/computer and information sciences/software]]

	'''EU Programme:'''		'''EU Programme:'''
	[[Programme::Horizon 2020]]		[[Programme::Horizon 2020]]

Admin at 12:17, 21 October 2025

2025-10-21T12:17:52Z

← Older revision		Revision as of 12:17, 21 October 2025
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	==[[EU Project short name::Cosmos]]==		==[[EU Project short name::Cosmos]]==
	===[[EU Project full name::~~Optical point~~ of ~~care system for heart failure mass screening~~]]===		===[[EU Project full name::Connectome cost conservation model of skill learning]]===
	'''Full project details (EU Research results portal):''' [[CORDIS URL::https://cordis.europa.eu/project/id/661484]]		'''Full project details (EU Research results portal):''' [[CORDIS URL::https://cordis.europa.eu/project/id/661484]]

Admin: Created page with "==EU Project short name::Cosmos== ===EU Project full name::Optical point of care system for heart failure mass screening=== '''Full project details (EU Research results portal):''' CORDIS URL::https://cordis.europa.eu/project/id/661484 === '''Project description:''' === Diseases of the heart and circulatory system are the main cause of death in Europe (over 4 million deaths each year). In particular, heart failure (HF) accounts for almost 1.1 million deaths..."

2025-10-21T11:55:30Z

Created page with "==EU Project short name::Cosmos== ===EU Project full name::Optical point of care system for heart failure mass screening=== '''Full project details (EU Research results portal):''' CORDIS URL::https://cordis.europa.eu/project/id/661484 === '''Project description:''' === Diseases of the heart and circulatory system are the main cause of death in Europe (over 4 million deaths each year). In particular, heart failure (HF) accounts for almost 1.1 million deaths..."

New page

==[[EU Project short name::Cosmos]]==
===[[EU Project full name::Optical point of care system for heart failure mass screening]]===
'''Full project details (EU Research results portal):''' [[CORDIS URL::https://cordis.europa.eu/project/id/661484]]

=== '''Project description:''' ===
Diseases of the heart and circulatory system are the main cause of death in Europe (over 4 million deaths each year). In particular, heart failure (HF) accounts for almost 1.1 million deaths each year. In early ’90 there was the formal recognition that inflammatory mediators are activated in the setting of HF by a sentinel description of inflammatory cytokines in patients with heart failure. After that, a growing interest in the role of biomarkers in regulating cardiac structure and function, particularly regarding their potential role in disease progression in heart failure, raised up. Nowadays, there are evidences on that. Generally, biomarkers are determined mostly in plasma or in blood, rather than in saliva. In fact, despite of that very few of them have been currently studied in saliva, saliva has to be considered as an important diagnostic and prognostic medium for minimally invasive tools. Indeed a great progress in disclosing the complete salivary proteome has carried to the identification of more than 3000 different proteins. Scope of this project is to develop a tool for HF-biomarkers detection through saliva. The idea is to combine the knowledge of the experienced researcher in microelectronics and CMOS imagers with the competences of the hosting laboratory on bioMEMs for biomarkers immobilization to develop an innovative point-of-care system for a fast and precise detection of HF-biomarkers. To this end the hosting institution and the experienced researcher complete each other and make the research and development on this cross related filed feasible. The proposed device will allow a mass screening for the prevention of HF and other pathologies related to the cardiovascular system.Within this project, the experienced researcher will be able both to enlarge her knowledge in the design of CMOS imagers by implementing innovative photon detection techniques and to approach a growing branch of microelectronics, such as the bioMEMs one.

'''EuroVoc IDs:''' [[EuroVoc ID::/natural sciences/biological sciences/biochemistry/biomolecules/proteins/proteomics]]

'''EU Programme:'''
[[Programme::Horizon 2020]]